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S1 1990 (Volume 68)
Quarterly Article
Harold Edgar
David J. Rothman
Oct 14, 2026
September 2026
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AIDS is systematically changing attitudes and practices regarding the regulation and use of drugs. The complex framework and rigorous research protocols developed by the Food and Drug Administration prior to the 1980s to minimize risk to subjects is shifting in the epidemic’s wake to maximize innovation. The FDA has adopted new procedures hastening access to investigational drugs and easing drug importation for personal use, which, in effect, transfers decisions about the benefits and risks of drugs from the agency’s staff to patients and their physicians. While the FDA’s tilt toward embracing consumer rights may continue in the near future, disappointing results could prompt the agency to reassert its authority in controlling drug policy more restrictively.
Author(s): Harold Edgar; David J. Rothman
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Volume 68, Issue S1 (pages 111–142) Published in 1990