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September 2016 (Volume 94)
Matthew J. Page
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In 1978, the distinguished professor of psychology Hans Eysenck delivered a scathing critique of what was then a new method, that of meta-analysis, which he described as “an exercise in mega-silliness.” A provocative article by John Ioannidis in this issue of the journal suggests that “mega-silliness” may be an appropriate characterization of what the meta-analysis literature has become. With surveys of the PubMed database and other empirical evaluations, Ioannidis paints a disturbing picture of the current state of affairs, where researchers are producing, in epidemic proportions, systematic reviews and meta-analyses that are redundant, misleading, or serving vested interests.
Author(s): Matthew J. Page and David Moher
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Volume 94, Issue 3 (pages 515–519) DOI: 10.1111/1468-0009.12211 Published in 2016
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The Milbank Quarterly’s multidisciplinary approach and commitment to applying the best empirical research to practical policymaking offers in-depth assessments of the social, economic, historical, legal, and ethical dimensions of health and health care policy.