Quarterly Topic

Opioid Use Disorder

Content Type:

  • The Largest Program for Opioid Use Disorder in a Statewide Carceral System: A Collaborative Multi-Agency Initiative

    Quarterly Article

    The Largest Program for Opioid Use Disorder in a Statewide Carceral System: A Collaborative Multi-Agency Initiative

    August 2025 ASHLY E. JORDAN RABIAH GAYNOR CAROL MOORES YOLANDA CANTY CHINAZO O. CUNNINGHAM

    In the United States, substance use disorder (SUD) is a significant public health and public safety challenge. Up to two-thirds of individuals who are incarcerated meet SUD criteria, compared with 16.7% of the general population. Individuals who have opioid use disorder (OUD) are also overrepresented in criminal legal settings: approximately 15.0% to 30.0% of individuals who are incarcerated have OUD, compared with 3.7% of the general population. Furthermore, individuals who are incarcerated are at high risk for fatal overdose both inside carceral facilities and upon reentry to the community. Overdose is the third leading cause of death in jails, and overdose deaths have increased more than six times over the past two decades in prisons. Among those reentering the community, fatal overdose is the leading cause of death. The risk of fatal overdose within the first two weeks following reentry is more than 100 times higher than in the general US population. More

  • Maximizing the Public Health Benefits of Opioid Settlements: Policy Recommendations for Equity, Sustainability, and Impact

    Quarterly Article

    Maximizing the Public Health Benefits of Opioid Settlements: Policy Recommendations for Equity, Sustainability, and Impact

    July 2025 BRANDON D. L. MARSHALL Kristen Pendergrass Sara Whaley

    The US overdose crisis is one of the most severe and devastating public health problems of the 21st century. Since 1999, more than one million Americans have lost their lives to accidental drug overdose. More

  • Laws Governing Substance Use During Pregnancy: Next Steps for Health Equity Research

    Quarterly Article

    Laws Governing Substance Use During Pregnancy: Next Steps for Health Equity Research

    July 2025 Hannah L.F. Cooper Anna L. Mullany Snigdha Peddireddy Simone Wien Melvin "Doug" Livingston Whitney S. Rice Anne L. Dunlop Michael R. Kramer Madison Haiman Lasha S. Clarke Natalie D. Hernandez-Green Angélica Meinhofer

    See all articles in the special issue, Mental Health and Substance Use Challenges Facing the United States: What Can State Policymakers… More

  • Integrating Mental Health and Substance Use Treatment With Emergency and Primary Care: The Case of Opioid Use Disorder and Suicide

    Quarterly Article

    Integrating Mental Health and Substance Use Treatment With Emergency and Primary Care: The Case of Opioid Use Disorder and Suicide

    July 2025 Noa Krawczyk Hillary Samples

    The United States is facing an ongoing mental health and substance use crisis. In 2023, 58.7 million US adults had a past-year mental illness, 46.3 million had a substance use disorder (SUD), and 20.4 million had both. More

  • Quarterly Opinion

    Opioid Settlements, Big Pharma, and Racial Disparities in the Opioid Epidemic

    July 2025 Jerel M. Ezell Sugy Choi

    Despite recent overall decreases in drug overdose deaths, racial disparities are persisting. This, coming against the backdrop of sweeping national opioid settlements, offers a reminder of the enduring potency of systemic racism in the face of what is otherwise a demonstrable public health success. More

  • Stemming the Tide of the US Overdose Crisis: How Can We Leverage the Power of Data Science and Artificial Intelligence?

    Quarterly Article

    Stemming the Tide of the US Overdose Crisis: How Can We Leverage the Power of Data Science and Artificial Intelligence?

    June 2025 Magdalena Cerdá DANIEL B. NEILL ELLICOTT C. MATTHAY JOHNATHAN A. JENKINS BRANDON D. L. MARSHALL Katherine Keyes

    People in the United States are dying at record numbers from overdose. Overdose deaths increased from fewer than 17,000 deaths in 1999 to an estimated 100,000 deaths approximately 25 years after, with a peak of almost 108,000 deaths in 2022. Racial/ethnic minoritized groups are now particularly affected: in 2023, the highest rates of overdose were among non-Hispanic Black and American Indian/Alaska Native Americans. Although overdoses increasingly involve both opioids and stimulants, opioids contribute to over three-quarters of all overdose deaths, primarily driven by illegally manufactured synthetic opioids like fentanyl. More

  • Quarterly Opinion

    Invisible and Overlooked (Again): Older Adults, Ageism, and Substance Misuse

    April 2025 Harold A. Pollack Marissa “Mari” Mackiewicz Soham Sinha

    Given common physiological and social changes associated with aging, older adults face greater risks of substance-related harms than do younger adults who experience the same patterns of substance use. More

  • The Long Arc of Substance Use Policy Innovation in Medicaid: Looking Back, Looking Forward

    Quarterly Article

    The Long Arc of Substance Use Policy Innovation in Medicaid: Looking Back, Looking Forward

    April 2025 Brendan Saloner

    This Perspective examines the role of Medicaid in the innovation of substance use disorder (SUD) treatment. In 2023, an estimated 49 million Americans met criteria for an SUD and more than 100,000 people died of a drug overdose. Compared with the general population, people with SUD experience worse self-rated health, a higher burden of other chronic diseases, and more hospital care. More

  • Quarterly Article

    Impacts of State-Level Opioid Review Programs on Injured Workers and Their Health Care Providers: A Qualitative Study in Washington and Ohio

    June 2024 Tasleem J. Padamsee Courtni Montgomery Stefan Kienzle Jeremy B. Straughn Andrea Elmore Deborah L. Fulton-Kehoe Beryl Schulman Thomas M. Wickizer Gary M. Franklin

    Context: Unsafe prescribing practices have been among the central causes of improper reception of opioids, unsafe use, and overdose in the United… More

  • Quarterly Article

    The Legal Landscape for Opioid Treatment Agreements

    May 2024 Larisa Svirsky Dana Howard Martin Fried Nathan Richards Nicole Thomas Patricia J. Zettler

    Context: Opioid treatment agreements (OTAs) are documents that clinicians present to patients when prescribing opioids that describe the risks of… More